There are already many scenarios of accidental and intentional overdose with propoxyphene merchandise possibly by itself or together with other CNS depressants, which include Liquor. Fatalities in the initial hour of overdosage aren't unusual. Many of the propoxyphene linked deaths have occurred in sufferers with preceding histories of emotional disturbances or suicidal ideation/makes an attempt and/or concomitant administration of sedatives, tranquilizers, muscle relaxants, antidepressants, or other CNS-depressant prescription drugs. Never prescribe propoxyphene for patients who will be suicidal or have a background of suicidal ideation.
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